Diablo 4has quite the late-game grind, and if you’re looking to summon what the community refers to as “ladder bosses,” then you’ll need to come prepared. To that end, you must collect all ofDiablo 4’sboss materials before finally meeting these big bads offering Unique equipment.

That being said, here’s everyDiablo 4material you’ll need to summon their respective bosses, separated by difficulty.

All boss materials in Diablo 4

Every boss material inDiablo 4

Some bosses can only be summoned in World Tier IV (Torment), while others can be summoned in Tier III at lower costs. This will be mentioned.

Duriel, King of Maggots

Andariel, Maiden of Anguish

With all that out of the way, there is one more universal item you need if you’re trying to fight the Tormented versions of these bosses. While you need three times the amount for normal summoning materials, you need a Stygian Stone each time.

The best farm for Stygian Stones is to completethe newly introduced Infernal Hordesmode at Tier 7 and higher. Enemy levels will be significantly higher, but the best loot will start dropping around, including the Stones.

Diablo 4 Grigoire

Diablo 4 Grigoire location

Diablo 4 Varshan

Diablo 4 Varshan location

Diablo 4 Beast in the Ice

Diablo 4 Beast in the Ice location

Diablo 4 Zir

Diablo 4 Zir location

Diablo 4 Duriel fight